37
Pathogenic Mechanisms
34.
Sarks SH, Arnold JJ, Killingsworth MC, Sarks JP. Early drusen
formation in the normal and aging eye and their relation to age
related maculopathy: a clinicopathological study. Br J Ophthalmol
1999; 83 (3): 358-368.
35.
Gass JD. Drusen and disciform macular detachment and degen-
eration. Arch Ophthalmol 1973; 90 (3): 206-217.
36.
Bressler NM, Bressler SB, West SK, Fine SL, Taylor HR. The grad-
ing and prevalence of macular degeneration in Chesapeake Bay
watermen. Arch Ophthalmol 1989; 107 (6): 847-852.
37.
Bressler SB, Maguire MG, Bressler NM, Fine SL. Relationship of
drusen and abnormalities of the retinal pigment epithelium to the
prognosis of neovascular macular degeneration. The Macular Pho-
tocoagulation Study Group. Arch Ophthalmol 1990; 108 (10):
1442-1447.
38.
McLeod DS, Taomoto M, Otsuji T, Green WR, Sunness JS, Lutty
GA. Quantifying changes in RPE and choroidal vasculature in
eyes with age-related macular degeneration. Invest Ophthalmol
Vis Sci 2002; 43 (6): 1986-1993.
39.
Lutty G, Grunwald J, Majji AB, Uyama M, Yoneya S. Changes
in choriocapillaris and retinal pigment epithelium in age-related
macular degeneration. Mol Vis 1999; 5: 35.
40.
Sarks JP, Sarks SH, Killingsworth MC. Morphology of early
choroidal neovascularisation in age-related macular degeneration:
correlation with activity. Eye (Lond) 1997; 11 ( Pt 4): 515-522.
41.
Grossniklaus HE, Green WR. Choroidal neovascularization. Am J
Ophthalmol 2004; 137 (3): 496-503.
42.
Penfold PL, Madigan MC, Gillies MC, Provis JM. Immunological
and aetiological aspects of macular degeneration. Prog Retin Eye
Res 2001; 20 (3): 385-414.
43.
Anderson DH, Mullins RF, Hageman GS, Johnson LV. A role for
local inflammation in the formation of drusen in the aging eye.
Am J Ophthalmol 2002; 134 (3): 411-431.
44.
Chen J, Connor KM, Smith LE. Overstaying their welcome: de-
fective CX3CR1 microglia eyed in macular degeneration. J Clin
Invest 2007; 117 (10): 2758-2762.
45.
Kim SY, Sadda S, Pearlman J, Humayun MS, de Juan E Jr, Me-
lia BM, Green WR. Morphometric analysis of the macula in eyes
with disciform age-related macular degeneration. Retina 2002; 22
(4): 471-477.
46.
Jalkh AE, Avila MP, Trempe CL, McMeel JW, Schepens CL.
Choroidal neovascularization in fellow eyes of patients with ad-
vanced senile macular degeneration. Role of laser photocoagula-
tion. Arch Ophthalmol 1983; 101 (8): 1194-1197.
47.
Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, Haynes C, Hen-
ning AK, SanGiovanni JP, Mane SM, Mayne ST, Bracken MB,
Ferris FL, Ott J, Barnstable C, Hoh J. Complement factor H poly-
morphism in age-related macular degeneration. Science 2005; 308
(5720): 385-389.
48.
Yang Z, Camp NJ, Sun H, Tong Z, Gibbs D, Cameron DJ, Chen
H, Zhao Y, Pearson E, Li X, Chien J, Dewan A, Harmon J, Bern-
stein PS, Shridhar V et al. A variant of the HTRA1 gene increases
susceptibility to age-related macular degeneration. Science 2006;
314 (5801): 992-993.
49.
Allikmets R, Dean M. Bringing age-related macular degeneration
into focus. Nat Genet 2008; 40 (7): 820-821.
